GPU Accelerated Cryo-Electron Microscopy
Relion is an image processing software designed specifically for cryo-electron microscopy (cryo-EM). Developed by the group of Sjors Scheres at the MRC Laboratory of Molecular Biology, the Relion framework is revolutionizing the cryo-EM field. It is a stand alone computer program built for the refinement of macromolecular structures by single-particle analysis of electron cryo-microscopy data. Relion employs an empiracal Bayesian approach for refinement of multiple 3D reconstructions or 2D class averages. With alternative approaches often relying on user expertise for the tuning of parameters, Relion can find an optimal way of filtering the data automatically.
Pipeline in Biological Cryo-EM
1.
Biochemical
Preparation
2.
Cryo-EM Sample
Preparation
3.
Imaging
4.
Data
Collection
5.
Image
Processing
6.
Reconstruction
7.
Structural
Analysis
8.
Model
Exxact GPU system accelerates the image processing, reconstruction, structural analysis, and modeling procedures for biological cryo-em.
Relion Iteration GPU vs CPU Comparison
Performance metrics for Relion (4x GPU Workstation vs 280x CPU Core Cluster)
Relion GPU Systems
Our solutions are specced to provide maximum GPU-accelerated performance for Relion 2.0 users. All Exxact Relion GPU systems feature the most of up-to-date Relion 2, Motioncorr, MotionCor2, Gctf, CTFFind4, ResMap software.
Quantum TXR431-2000R
• 2x Intel Xeon E5-2600 v3/v4 Haswell/Broadwell Processors
• Up to 512GB DDR4 Memory
• Up to 4x NVIDIA Tesla Pascal GPUs
• 8x hot-swap 3.5" drives bays + 3x fixed 5.2.5" drives bays + 1x fixed 3.5" drive bays
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Quantum TXR432-0512R
• 1x Intel Core i7-5960X Processor Extreme Edition (20M Cache, up to 3.50 GHz); Optional Xeon Processor
• 32GB DDR4 Memory installed (Supports up to 128GB DDR4; 256GB with optional Xeon Processor)
• Up to 4x NVIDIA Tesla Pascal GPUs
• Tower/4U Rackmount Convertible
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Quantum TXR431-1500R
• 2x Intel Xeon E5-2600 v3/v4 Haswell/Broadwell EP Processors (up to 130W TDP)
• Up to 1.5TB DDR4 Memory
• Up to 8x NVIDIA Tesla Pascal GPUs
• 24x 2.5" hot-swappable SAS/SATA/SSD bays
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Quantum TXR233-1000R
• 2x Socket 2011-3 Intel Xeon E5-2600 v3/v4 Haswell/Broadwell processors
• Up to 1024GB Memory
• Up to 4x NVIDIA Tesla Pascal GPUs
• 8 x SATA3 6Gb/s ports Optional: SAS 6G RAID Card
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The EXXACT Solution Advantage
NVIDIA Elite Solution Provider:
As an Elite Solution Provider with NVIDIA, Exxact Corporation works closely with the NVIDIA team to ensure seamless factory development and support. We pride ourselves on providing value-added service standards unmatched by our competitors.
Exxact offers multiple form factors should your computing needs change down the road, minimizing growing pains due to unpredictability.
Each GPU Workstation is engineer built and meticulously tested for precision and performance. We stand behind our products by offering 3-year warranty on our GPU Workstations.
Exxact GPU Workstations are built by in-house engineers and individually customizable for peak performance tailored to solving your unique and complex computing challenges.
Besides remote assistance, Exxact also offers on-site technical support including 8x5 NBD, 24x7 NBD, 24x7x4hr.